Device Solutions to Peripheral and Neurovascular Diseases

Publication Date: 21 February, 2022

Source: Headline Daily


Peripheral artery disease in the legs or lower extremities is the narrowing or blockage of the vessels that carry blood from the heart to the legs. It is primarily caused by the build-up of fatty plaque in the arteries, which is called atherosclerosis.

At times, the process of calcium accumulation in the blood vessels results in stiff and hard plaques that obstruct the blood flow.

OrbusNeich® produces a range of peripheral interventional medical devices for minimally invasive procedures, with a focus on high pressure and specialty scoring balloons to manage calcified plaque which is difficult to open. With good recognition about our balloons’ performance from key opinion leaders from around the world, we launched our high-pressure angioplasty balloon for peripheral application in the United States and received FDA approval in June 2021. The unique features of these balloons make it an ideal choice in the treatment of challenging peripheral artery disease, including hard calcified plaques.

Another exciting area that we have put our focus on is a new generation drug eluting balloon with accurate deliverability of active pharmaceutical ingredient to the blockage to sustain the opening of a blocked artery for a longer duration.  Different from the current mainstream paclitaxel-carrying balloons, we applied a proprietary drug-loading and coating technique to carry sirolimus, a drug that has been widely used in all latest drug eluting coronary stents with proven record of its long-term safety and efficacy.

With our expertise in catheter-based technology, we are developing a neuro microcatheter for the transport of endovascular coiling for the embolization of brain aneurysms that cause haemorrhagic stroke, an intracranial angioplasty balloon to open blocked artery for ischemic stroke, and various neuro catheter devices for thrombus removal.

In recent years, with the advances in imaging technology and its increasing application in clinical practice, the intravascular system in a human body can be better seen and the detection rate of vascular diseases can be improved. As the applications of A.I. in the medical field increase, the development of automation of imaging systems and analytics software will accelerate in the coming years and help doctors to efficiently achieve more accurate diagnoses of peripheral and neurovascular diseases.