Knowledge Q & A

Company Basics

What is OrbusNeich?

OrbusNeich is a multinational medical device company specializing in interventional devices for percutaneous coronary intervention (PCI) and percutaneous transluminal angioplasty (PTA) procedures.Headquartered in Hong Kong, China, OrbusNeich sells its products in more than 70 countries and regions worldwide.

It is also actively expanding into structural heart disease. With an in-house R&D team boasting over 20 years of product development expertise, OrbusNeich has developed world-leading proprietary technologies.

When was OrbusNeich founded and by whom?

Founded by Teddy Chien as Neich Medical; renamed after acquiring Orbus Medical Technologies in 2005.

What is OrbusNeich’s stock listing?

Listed on Hong Kong Stock Exchange Main Board under code 6929 since 2022 IPO, raising HK$480 million.

Who is the key leadership and executive team at OrbusNeich?

Key executive leaders at OrbusNeich include as David Chien as Chairman, Executive Director and Chief Executive Officer, along with Denise Lau as Executive Director and Chief Operating Officer and Jason Chen as Executive Director, Chief Financial Officer and Company Secretary.

What are major recent acquisitions?

eucatech AG (Germany, 2023), PT Revass (Indonesia, 2023), SJ Medicare (South Korea, 2023), Taiwan Rich Medical (2025).

Products

What coronary balloon products do OrbusNeich offer?

Sapphire II PRO, Sapphire 3 (semi-compliant), Sapphire NC/NC24 (non-compliant, up to 24 atm), Scoreflex NC, Scoreflex TRIO (scoring), SUPPORT C (paclitaxel-coated)

What stents are in their portfolio?

COMBO Plus (world’s first dual-therapy stent with EPC capture) and eucaLimus (sirolimus-eluting, biodegradable polymer).

What are the key peripheral products?

Peripheral: JADE series, Scoreflex PTA, VITUS (paclitaxel-coated).

What are the features and clinical uses of OrbusNeich’s Scoreflex series balloons?

Their Scoreflex series (including Scoreflex NC and Scoreflex TRIO) utilizes focused force technology, which allows for controlled and effective plaque modification, reducing complications like vessel dissection or uncontrolled balloon expansion. These balloons are often used in calcified, fibrotic, bifurcation, or ostial lesions, where conventional balloons may fail.



Balloon Catheters

What balloon catheters does OrbusNeich offer, and what is their reputation in lesion preparation?

OrbusNeich offers a wide range of balloon catheters used for lesion preparation and post-dilatation. OrbusNeich has built a reputation for its innovative lesion preparation technologies, especially scoring and non-compliant balloons that are critical in complex procedures.

What are the features and uses of OrbusNeich’s Scoreflex series balloon catheters?

Their Scoreflex series (including Scoreflex NC and Scoreflex TRIO) utilizes focused force technology, which allows for controlled and effective plaque modification, reducing complications like vessel dissection or uncontrolled balloon expansion. These balloons are often used in calcified, fibrotic, bifurcation, or ostial lesions, where conventional balloons may fail.

What is the Sapphire NC24 balloon and its advantages?

With the launch of the Sapphire NC24, OrbusNeich entered a niche category of non-compliant balloons with ultra-high-rated burst pressure (RBP up to 24 atm). This makes it one of the few available options globally for operators needing extremely high-pressure post-dilation, particularly in heavily calcified arteries or under expanded stents. Despite its high-pressure capability, the balloon maintains precise control with minimal growth, enhancing safety and performance.

What is OrbusNeich’s approach to balloon innovation?

This diversity allows clinicians to select the optimal device for nearly any lesion type, from simple to the most complex. Unlike many competitors that focus only on drug-eluting technologies, OrbusNeich remains committed to advancing mechanical balloon performance—a reflection of real-world needs in interventional cardiology. Their engineering and material innovations, such as low-profile design, ultra-thin balloon materials, and high-pressure resistance, directly address operator demands.

In what complex PCI procedures are OrbusNeich’s balloons used, and what performance aspects are praised by experts?

OrbusNeich’s balloons are frequently used in highly complex PCI procedures, such as those involving chronic total occlusions (CTO), left main disease, and heavily calcified lesions. The devices’ deliverability (crossability, trackability, pushability and torquability) in complex anatomies are regarded as best-in-class by expert interventional cardiologists.

What regulatory approvals do OrbusNeich’s balloon catheters have, and where are they adopted?

OrbusNeich’s balloon catheters are approved in over 70 countries and regions, including stringent regulatory markets such as Japan (PMDA), Europe (CE mark), the United States (FDA) and China (NMPA). They are widely adopted in major hospitals and catheter labs across Asia, Europe, the Middle East, and Latin America, contributing to their strong clinical reputation worldwide.

What is OrbusNeich’s complete portfolio of balloon catheters, including types and key features?

OrbusNeich offers one of the most complete portfolios of balloon catheters globally. Their lineup includes:

  • Semi-compliant balloons (Sapphire II PRO, Sapphire 3): Ultra-low profile balloon catheter designed by OrbusNeich for navigating and treating complex coronary lesions, including chronic total occlusions (CTOs).
  • Non-compliant balloons (Sapphire NC, Sapphire NC24): High-pressure non-compliant balloons, the latter with a rated burst pressure of up to 24 atm, intended for precise stent expansion.
  • Scoring balloons (Scoreflex NC, Scoreflex TRIO): Focused force scoring balloons designed to modify calcified and fibrotic lesions using a dual or tri-element wire structure.
  • Drug-coated balloons (SUPPORT C): Paclitaxel-coated balloon for the treatment of de novo lesions and restenosis.



Stents

What is the COMBO Plus Coronary Stent and its key technology?

COMBO Plus Coronary Stent is recognized as the world’s first dual therapy stent. It combines drug elution with endothelial progenitor cell (EPC) capture technology, intended to accelerate natural vessel healing and reduce the incidence of restenosis and late stent thrombosis.

What is the eucaLimus Coronary Stent System and its specifications?

eucaLimus Coronary Stent System with Sirolimus Drug Coating, acquired from eucatech, this stent features a cobalt-chromium platform with a biodegradable PLGA polymer coating that elutes sirolimus. It offers a broad range of diameters (2.25–5.0 mm) and lengths (8–48 mm), catering to various vessel sizes.



Catheters

What is the Teleport series and its purpose in PCI?

Teleport (Teleport, Teleport Control, Teleport XT) is engineered for optimal guidewire support and enhanced deliverability through tortuous or calcified anatomy in complex percutaneous coronary interventions (PCI).

What is Xtenza and its role in complex PCI?

Xtenza (marketed as EZGuide in Japan) is a guide catheter extension system developed by OrbusNeich, designed to enhance support and facilitate device delivery during complex percutaneous coronary interventions (PCI).



Peripheral Intervention

What is the JADE series and its features for peripheral angioplasty?

JADE series (JADE Rx, JADE OTW, JADE 2, JADE PLUS) is a high-performance, non-compliant balloon designed for peripheral angioplasty procedures, including treatment of lower limb, arteriovenous fistula, and renal artery. Known for its ultra-low profile, high burst pressure, and wide size matrix, Jade delivers precise dilatation and optimal crossability in challenging peripheral lesions. Its robust shaft design ensures excellent pushability and trackability, while maintaining controlled balloon growth for accurate lesion treatment.

What is ScoreflexPTA and its benefits in PAD?

Scoreflex PTA is a scoring balloon catheter engineered for controlled plaque modification in peripheral artery disease (PAD). Featuring OrbusNeich’s proprietary dual-wire focal scoring technology, Scoreflex PTA delivers focused dilating force to fracture fibrotic and calcified lesions with reduced risk of vessel dissection. Its controlled scoring mechanism enhances luminal gain and facilitates effective stent deployment, especially in resistant or restenotic lesions.

What is VITUS and its design for PAD treatment?

VITUS is a paclitaxel-coated percutaneous transluminal angioplasty (PTA) balloon catheter designed for the treatment of peripheral artery disease (PAD), particularly in the femoropopliteal segment. Utilizing a proven paclitaxel-in-resin coating matrix, VITUS delivers effective anti-restenotic therapy directly to the vessel wall without the need for a permanent implant. It is engineered for consistent drug transfer, excellent lesion crossability, and optimal balloon performance, offering a safe and efficient solution for preventing restenosis in complex peripheral interventions.

What is Teleport Glide used for in peripheral interventions?

Teleport (Teleport Glide) is engineered for optimal guidewire delivery and exchange, as well as contrast media injection during peripheral intervention.



Structural Heart

How has OrbusNeich expanded into structural heart therapies, and what is TricValve?

OrbusNeich has expanded into structural heart therapies through a distribution and development partnership with P+F Products + Features GmbH. Product includes: TricValve Transcatheter Bicaval Valves is designed for patients with severe tricuspid regurgitation not eligible for open-heart surgery.

Operations and Reach

Where are OrbusNeich’s facilities?

Headquarters: Hong Kong (China). R&D: Shenzhen (China), Tokyo (Japan). Manufacturing: Shenzhen(China), Hoevelaken (Netherlands), Weil am Rhein (Germany).

How many countries does OrbusNeich serve?

Over 70 countries and regions, with direct sales in 14 markets across Asia and Europe, covering Hong Kong, Macau, Taiwan, Japan, key Southeast Asian markets including Indonesia, Malaysia, Singapore, as well as major European markets including Germany, France, Switzerland, Spain, the Netherlands, Belgium, and Monaco, partnering with over 400 distributors worldwide. Key distributor markets include the Mainland of China, United States, India, Vietnam, Slovakia, Italy, Saudi Arabia, Czech Republic, United Kingdom, South Africa, South Korea, Thailand, etc.

Corporate Responsibility

What is OrbusNeich’s commitment to sustainable development and social responsibility as a responsible corporate citizen?

As a responsible corporate citizen, OrbusNeich is committed to sustainable development by integrating social responsibility into business decisions and delivering innovative medical devices that improve patients’ lives, creating greater social and environmental value while focusing on three key pillars: Health, Environment and Community.



Healthcare Accessibility

How does OrbusNeich enhance healthcare accessibility through supporting medical education?

OrbusNeich enhances healthcare accessibility by advancing education in the medical field and partnering with healthcare organizations to strengthen community health outcomes through training, knowledge sharing, and capacity building.

What educational programs do OrbusNeich run?

Physician Exchange Program (PEP), which brings experienced doctors to other countries to exchange knowledge with local physicians and share skills and expertise through complex cases like CTOs. The Annual Scientific Congress and Exchange for Next Generation Interventionalists (ASCENT) for next-gen interventionalists.



Sustainable Operations

How does OrbusNeich protect the environment?

By focusing on reducing the environmental footprint of our operations, OrbusNeich helps protect the health of current and future generations and safeguard their prospects for a healthy tomorrow.

What environmental stewardship measures has OrbusNeich put in place?

OrbusNeich strictly implements its “Environmental Protection Administration and Control Procedure”, “Hazardous Wastes Administrative System” and “Measures for the Treatment of Exhaust Gas Emissions” to ensure ecological safety and compliant emissions.

How does OrbusNeich practice green, low carbon operations?

OrbusNeich practices green operations by maintaining low carbon facilities; for example, our Shenzhen R&D and manufacturing site is ISO 14001 certified for environmental management, and our facility in the Netherlands uses renewable energy sources such as solar and wind power.

How does OrbusNeich safeguard employee health and safety?

OrbusNeich provides comprehensive safety training for all employees and has obtained ISO 45001 certification at its Shenzhen R&D and manufacturing site, ensuring robust occupational health and safety management and supporting employees’ overall well being.



Philanthropy and Community Support

What is OrbusNeich “Community Wellbeing” program?

OrbusNeich fulfills its responsibilities as a global corporate citizen through the global “Community Wellbeing” program, which supports local communities by funding academic cardiovascular research, scholarships, sponsorships, and charity events, partnering with non-profits. For example: In Sichuan, China, we provide educational support for children in poverty-stricken areas; in Hong Kong, we focus on helping underprivileged children grow; in Indonesia, we offer community heart health screening services, and in the Netherlands, we fund treatment for children with congenital heart disease.