VITUSTM

Paclitaxel Coated PTA Catheter

Designed for
Optimized Drug Transfer

G-70-2349 Rev04

4P Concept · 01

Precise Deliverability

  • Low profile and good deliverability for crossing challenging peripheral lesions
VITUS catheter low-profile tip
4P Concept · 02

Predictable Coating

VITUS balloon uniform drug coating
  • Uniform drug coating with Butyryl-Tri-Hexyl Citrate (BTHC) excipient
  • Enables high bioavailability of Paclitaxel
  • Uniform vessel wall coverage at target vessel
4P Concept · 03

Persistent Tissue Absorption

Microcrystalline Paclitaxel acts as a reservoir for sustained drug release over 30 days.

Paclitaxel Arterial Tissue Level
Paclitaxel arterial tissue level line chart versus competitors

Data on file.

Microcrystalline Paclitaxel
SEM image of microcrystalline Paclitaxel

Data on file.

4P Concept · 04

Prompt & Safe Drug Delivery

BTHC as a high drug retention excipient protects against premature drug wash-off for optimal drug absorption into the vessel wall.

Pure Paclitaxel particle illustration

Pure Paclitaxel

→
Drug carrier matrix of Paclitaxel and BTHC illustration

Drug Carrier Matrix
Paclitaxel and BTHC

G-70-2997 Rev01